Pentazocine

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This article describes the pharmacology and clinical uses of the opioid agonist-antagonist pentazocine. Pentazocine is widely used around the world despite its considerable side-effects and tendency to cause dependency. It still has a useful function to play in the management of moderate to severe pain when used intravenously or intramuscularly, but should not replace morphine or pethidine if available.

Karen Henderson