June 1, 2000
Chronic Renal Failure and Anaesthesia (Update 11)
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Chronic Renal Failure (CRF) may be caused by primary renal disease or by systemic diseases which also affect the kidney. A decrease in nephron function occurs and can lead to a typical clinical pattern. CRF only becomes biochemically evident when less than 40% of the nephrons are functioning. Dialysis (either peritoneal or haemodialysis) is generally not required until less than 10% of nephrons are functioning. Patients with CRF are more likely to have associated atheroma formation and hypertension.
Penny Stewart, Debbie Harris
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